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会议详情 |
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发票类型：增值税普通发票 增值税专用发票
我们代表组委会热情地邀请您参加于2014年9月27日 - 29日在中国上海召开的《2014年国际病毒进入抑制剂研讨会》（2014 International Symposium on Virus Entry Inhibitors，ISVEI）。本次会议是由医学分子病毒学教育部/卫生部重点实验室及中国南方医科大学药学院（广州）联合主办，其主题为“御敌于门外”。
在20世纪90年代初，数个衍生于HIV-1 gp41 HR2（或CHR）结构域衍生的多肽被发现是高效的HIV融合/进入抑制剂。其中的一个多肽，T20（通用名：恩夫韦肽; 商品名：Fuzeon）于2003年获得美国FDA的批准成为第一个HIV融合 / 进入抑制剂，用于治疗艾滋病毒感染或艾滋病患者，特别适用于那些对现有的抗逆转录病毒药物的无反应者。这些抗HIV多肽的发现开辟了一个全新的方向 – 研究病毒进入抑制剂来拮抗包膜病毒，如副粘病毒[包括呼吸道合胞病毒（RSV）、人副流感病毒类型3（HPIV-3）、麻疹病毒（MV）、仙台病毒、Menangle病毒、腮腺炎病毒和新城疫病毒等]、流感病毒、登革热病毒、C型肝炎病毒（HCV）、以及那些导致新发传染病疾病的病毒 （如埃博拉病毒、Nipah virus、Hendra virus、SARS冠状病毒和MERS冠状病毒）。
在过去的十年中，在病毒融合 / 侵入抑制剂，包括小分子、多肽和蛋白质（包括抗体）的研究取得了前所未有的快速进展。本次研讨会将聚焦于病毒进入靶细胞的机制和病毒进入抑制剂的研究，将给与会者提供很好的机会来与来自不同学科（包括病毒学、药物学、免疫学、分子生物学、生物化学、病理学和临床）的国际同行们深入地探讨病毒进入抑制剂领域的关键科学问题。
上海是中国第一大城市，中国的经济和金融中心，繁荣的国际大都市。其位于太平洋西岸，亚洲大陆东沿，中国南北海岸中心点，长江和黄浦江入海汇合处。其周边城市，如杭州、苏州、义乌、无锡、昆山等被为认为是具有中国传统特色的小城市。
我们希望本次研讨会将为您提供会见老朋友和结交新朋友的机会，并在学术交流和建立合作关系等方面获益匪浅。
美丽的上海欢迎您！
会议日期：2014年9月27-29日，2014年9月27日报到。
会议地点：复旦大学基础医学院
地址：上海市徐汇区东安路130号东院明道楼报告厅
主办单位：
医学分子病毒学教育部/卫生部重点实验室
南方医科大学药学院（广州）
| International Symposium on Virus Entry Inhibitors (ISVEI) | |
| Shanghai Medical College, Fudan University ~ Shanghai, China | |
| September 27-29, 2014 | |
| Saturday, September 27 | |
| 2014 (International Conference Hall at the 1st floor, Mingdao Building, | |
| Shanghai Medical College; 上海医学院明道楼一楼国际会议报告厅) | |
| 16:00-21:00 | Registration |
| 18:00-19:30 | Welcome Reception and Buffet Dinner |
| (Shanghai Pine City Hotel, 上海青松城大酒店) | |
| Sunday, September 28 | |
| 2014 (International Conference Hall at the 1st floor, Mingdao Building, | |
| Shanghai Medical College; 上海医学院明道楼一楼国际会议报告厅) | |
| 7:00-18:00 | Registration and Poster set-up |
| 8:30-8:50 | Opening of the 2014 International Symposium on Virus Entry Inhibitors |
| Opening remarks from ISVEI Organizing Committee: | |
| Dr. Shibo Jiang, Director of Institute of Medical Microbiology, Fudan University | |
| Dr. Zhenghong Yuan, Vice President of Fudan University | |
| Dr. Qiqun Tang, Dean of Basic Medical College, Fudan University | |
| Dr. Shuwen Liu, Dean of Pharmaceutical College, Southern Medical University | |
| 8:50-9:30 | Dr. Shibo Jiang, Shanghai Medical College, Fudan University |
| Opening lecture: “Twenty Years of Developing Virus Entry Inhibitors” | |
| 9:30-10:00 | Take group pictures and refreshment break |
| 10:00-12:00 | Session I: HIV Entry and Entry Inhibitors (I) |
| Chairs: Drs. Tom Gallagher and Keliang Liu | |
| 10:00-10:30 | Asim K. Debnath, Ph.D., Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY, USA. |
| Keynote lecture: “Plugging the Hole in HIV-1 gp120 – Designing Inhibitors to Prevent Virus Entry” | |
| 10:30-10:55 | Dr. Dong Xie, Frontier BioSciences, Nanjing, China |
| “The Design and Bioactivity Evaluation of New HIV-1 Fusion Inhibitors” | |
| 10:55-11:20 | Dr. Keliang Liu, Department of Medicinal Chemistry, Beijing Institute of Pharmacology & Toxicology, Beijing, China. |
| “Design and Discovery of Potent HIV-1 Fusion Inhibitors” | |
| 11:20-11:45 | Dr. Yuxian He, the AIDS Research Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. |
| “The M-T Hook Structure and HIV-1 Fusion Inhibitors” | |
| 11:45-12:05 | Dr. Bing Chen, Boston Children's Hospital/Harvard Medical School, MA, USA |
| “Small-Molecule Inhibitors Targeting a Fusion Intermediate State of HIV-1 gp41” | |
| 12:05-13:30 | Lunch served |
| 13:30-17:50 | Session II: Entry and Entry Inhibitors of HCV, Influenza Virus, HPV, Coronavirus, EV71, and Poxvirus |
| Chairs: Drs. Asim K. Debnath and Min Luo | |
| 13:30-14:00 | Dr. Flossie Wong-Staal, iTherX Pharmaceuticals, Inc., San Diego, CA, USA |
| Keynote lecture: “Preclinical and Clinical Studies of an HCV Entry Inhibitor Targeting the Scavenger Receptor B1” | |
| 14:00-14:25 | Dr. Shuwen Liu, Pharmaceutical Science, Sourthen Medical University, Guangzhou, China |
| “Influenza Virus Entry Inhibitors” | |
| 14:25-14:50 | Dr. Min Luo, Department of Chemistry, Georgia State University, Atlanta, GA, USA |
| “Entry Inhibitors Yhat Reduce Membrane Fusogenicity of Influenza Virus” | |
| 14:50-15:15 | Dr. Xia Yang, Jingbo Pharmaceutical Inc, Taiyuan, Shangxi Provence, China. |
| “JB01 - an HPV Entry Inhibitor against HPV Infection” | |
| 15:15-15:45 | Refreshment break |
| 15:45-16:10 | Dr. Tom Gallagher, Department of Microbiology and Immunology, Loyola University Medical Center, Maywood, IL, USA. |
| “Synergistic Anti-coronavirual Activity IFITM3 and Fusion-inhibiting Heptad Repeat Peptides | |
| 16:10-16:35 | Dr. Stanley Perlman, Departments of Microbiology and Pediatrics, University of Iowa, Iowa City, USA. |
| “Development of Mouse Models Useful for Studying MERS-CoV Entry Inhibitors and Pathogenesis” | |
| 16:35-17:00 | Dr. Xinquan Wang, Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, China. |
| “MERS Coronavirus Cell Entry: from Structure to Neutralizing Antibody” | |
| 17:00-17:25 | Ralf Altmeyer, Ph.D., Institut Pasteur Shanghai, Chinese Academy of Sciences, Shanghai, China. |
| “The Approved Pediatric Drug Suramin Identified as an EV71 Entry Inhibitor” | |
| 17:25-17:50 | Dr. Andy Qigui Yu, Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA. |
| “Poxvirus Tropism for Primary Human Leukocyte Subsets” | |
| 17:50 | Take bus to XiaoNanGuo Restaurant |
| 19:00-20:30 | Banquet at XiaoNanGuo Restaurant |
| Monday, September 29 | |
| 2014 (International Conference Hall at the 1st floor, Mingdao Building, | |
| Shanghai Medical College; 上海医学院明道楼一楼国际会议报告厅) | |
| 7:00-10:00 | Registration |
| 8:30-12:30 | Session III: HIV Entry and Entry Inhibitors (II) |
| Chairs: Drs. Bin Chen and Yuxian He | |
| 8:30-9:00 | Dr. Yechiel Shai, Department of Biological Chemistry, the Weizmann Institute of Science, Rehovot, Israel |
| Keynote lecture: “Lipo-peptides Derived from HIV gp41 Are potent Entry Inhibitors: Roles for the Peptide and the Lipid” | |
| 9:00-9:25 | Dr. Rogier W. Sanders, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. |
| “Mechanisms of HIV-1 Escape from Fusion and Anchor Inhibitors” | |
| 9:25-9:50 | Dr. Zhiwei Wu, Center for Public Health Research, School of Medicine, Nanjing University, China. |
| “Stopping HIV at the Gate - Multipurpose Prevention Technologies: a New Forefront Combating HIV, STD and Reproductive Health” | |
| 9:50-10:20 | Refreshment Break |
| 10:20-10:40 | Dr. Liying Ma, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. |
| “HIV-1 Envelope Variations, Viral Fitness and Their Impact on Application of HIV Entry Inhibitors” | |
| 10:40-11:00 | Dr. Jianjun Tan, College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China. |
| “Design, Synthesis and Activity Evaluation of Novel Peptide Fusion Inhibitors Targeting HIV-1 gp41” | |
| 11:00-11:20 | Dr. Weihua Li, Shanghai Institute of Planned Parenthood Research, WHO Collaborating Centre for Research in Human Reproduction, Shanghai, China |
| “Spermcidal Activity of B07, a CCR5 Antagonist-based HIV-1 Entry Inhibitor” | |
| 11:20-11:40 | Dr. Lan Xie, Department of Medicinal Chemistry, Beijing Institute of Pharmacology & Toxicology, Beijing, China. |
| “Small Molecule Fusion Inhibitors: Design, Synthesis, and Biological Evaluations of Substituted N-phenyl-2,5-dimethylpyrroles Targeting HIV-1 gp41” | |
| 11:40-12:00 | Closing comments |
| 12:00-13:30 | Lunch served |
参会费：1500元/人
会议注册费用包含:
2014年27-29日期间学术报告厅及展览区域的进入许可。
2014年27-29日的会议茶歇及午餐。
2014年9月27日的会议欢迎酒会。
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